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At the start of the game, you put one of them into play and shuffle the rest into the deck. Each disease has a different ability, and they affect all players. Disease cards don’t count as permanents, and whenever you draw one it goes into play immediately.

As your action in a turn, you can shuffle all Disease cards from play back into the deck - this is the only way to get rid of them, but it might be worth it...especially if all eight are in play!

Includes eight Disease cards:

Pox

Scurvy

Typhus

Beriberi

Fever

Sailor’s Bane

Sea-Sickness

Piratitis!